Pre~Breeding Screening


What do tests really tell breeders?


Rush2

Canine Diverisity Analyisis

Click the title above if you’d like to learn more about the Canine diversity Project and how it relates to our Poodle population and check out the links below to read more specificly each topic

cdp

BioMed Central Research Paper

 

ucdavis

Genetic Diversity in Standard Poodles Study


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Physical Tests:

CERF:

How to read a CERF evaluation:

OFA Hips:
PennHips:
Elbows:
Patellas:
Cardiac Echo:
Thyroid:
Brucelosis:
Sebaceous Adenitis:

chachachachanges

Genetic Tests:


What are DNA tests and are they reliable.

Progressive Retinal Atrophy (PRA): 

Degenerative Myelopathy (DM)This is an autosomal recessive disease with a mutation in the SOD1-A Gene.  It is adult-onset with ALS like symptoms:  progressive limb weakness, muscle loss, tremors and stumbling developing into spinal and hind end paralysis.  N/N= clear N/A=Carrier A/A= Affected

Von Willebrand’s Disease 1 (vWD1):  This is an autosomal recessive disease characterized by low production of von Willebrand’s factor which is a key component in the clotting cascade.  N/N= clear N/A=Carrier A/A= Affected

Neonatal Encephalopathy with Seizures (NEwS): This is an autosomal recessive developmental disease of the the brain.  It has a very early onset presenting before 7 weeks with a zero percent survival rate.  Affected puppies show progressive weakness, ataxia and ultimately seizures and death.  N/N= clear N/A=Carrier A/A= Affected

More recently developed tests

Macrothrombocytopenia (MTC):  This is an autosomal dominant disease with a mutation in the beta-1 tublulin gene causing the disease.  It is characterized by low platelet values and the presence of giant platelets in the circulation.  Unfortunately this form of thrombocytopenia doesn’t respond to treatment.  N/N= clear N/A=Carrier A/A= Affected

Osteochondrodysplasia (OCD):

Gangliosidosis (GM2):


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Poodle Disease currently with no available screening


Addisons Disease

Gastric dilatation volvulus (Bloat):

Epilepsy:

Squamous Cell Carcinoma (SCC):